.... Explains "Protection from Severe Disease" and Endless Reinfections
In the last section of my post from yesterday, I asked, why doesn’t
Paxlovid work for vaccinated people.
Try to stop and think for a minute. Ask yourself a question: why,
exactly, is Paxlovid not working in the vaccinated?
The problem is not with Paxlovid, it is the same medication as given to
the unvaccinated. The problem is with the immune systems of the vaccinated. The
vaccinated cannot clear Covid, while replication is temporarily paused by
Paxlovid. The unvaccinated can. Why?
It is a question that I would like to explore, as it may be key to multiple
reinfections of the vaccinated, as well as to “less severe disease”
that the vaccinated are having, while simultaneously having higher viral loads.
Both phenomena are explained by lack of immune reaction to Sars-Cov-2
from deprogrammed immune systems that were unset and imprinted by several mRNA
spike protein transfections.
Part of “severe disease” comes from cytokine storms, caused by an
overreaction of immune systems. Well, if immune systems are
deprogrammed, they will not overreact — not even react properly — and will not
clear the virus either. They will not prevent reinfections, as well.
A Twitter user @SimonBuresch, who saw my substack post, provided a link to a very interesting anonymous write-up from
Sep 2021. I am quoting it verbatim
below, because it is a very interesting thought that explains ALMOST everything
we are seeing. It is also notable for WHEN it was posted, which was almost
a year ago.
However, before you read the quoted article, I must point out that this
anonymous explanation may easily be not quite correct and things must be much
worse than “Mark L” is hypothesizing.
Specifically, it may be that mRNA vaccination unsets the entire immunity
and makes people more vulnerable to Covid, as well as to non-Covid “vaccinated
people illnesses” that they seem to get more easily, such as the notorious
“Australian Flu” that makes people bedridden
for 10 days. (normally flu
clears easily in 3-4 days). I have noticed those “vaccinated people illnesses”
in some of my acquaintances. This does not even bring up “monkeypox” or
“Crimean Congo” or other exotics. I consider that worse possibility, sometimes
described as VAIDS, to be more likely. In addition, “protection from
severe disease” also did not prove as durable. More on this later.
That said, I feel that I must present that interesting theory. It will stimulate my readers’ intellect and Mark L likely asked the
right questions. It explains that Covid vaccines create a tolerance to
spike protein, and because of it, the vaccinated do not have severe illness,
but also cannot clear the virus and cannot acquire immunity. (the bigger
question, of course, is whether the boosted can acquire immunity to anything
else besides Covid. Nobody answered that or even asked.) Again, please consider
the piece below critically, but appreciate the originality of Mark L’s thought
from Sep 2021.
The text below was NOT written by me.
mRNA Vaccines Elicit Immune Tolerance to Spike
Protein
Date: 2021-09-07 05:00 pm (UTC)
From: (Anonymous)
Something strange is clearly going on with regard to the vaccines, aside
from the high risk of adverse effects. Despite evidence that they provide
protection against symptomatic infection and severe illness, many countries
with the highest vaccination rates have the highest illness and hospitalization
rates, and the current wave of infection is both much stronger than would be
expected in the northern hemisphere summer and also failing to drop off rapidly
after a peak as occurred with past waves and the first Delta wave in India. In
Israel, where a booster campaign is well underway, positive cases continued to
rise even as hospitalizations leveled off, and the case rate is now among the
highest of any country on Earth.
Over the past few days I have developed a hypothesis that could help to
explain:
· High disease prevalence in regions with high uptake of genetic vaccines.
· Increasing disease prevalence following widespread booster vaccination
in Israel.
· High ratios of unvaccinated to vaccinated hospital patients.
· Much better vaccine protection against severe illness than against
infection.
· Maintained vaccine protection against severe illness over time despite
waning immunity.
· Inferior vaccine protection against infection compared to natural
immunity, despite comparable levels of neutralizing antibodies and T/B-cell
activation.
· Higher rates of asymptomatic infection among vaccinated people despite
limited testing.
· Political refusal to test asymptomatic vaccinated people for infection
under most circumstances.
The hypothesis is that genetic vaccines are inducing partial immune tolerance
to spike protein, likely through a regulatory T-cell response. If any
commenters know immunologists or vaccinologists, I would be very interested to
hear their thoughts with regard to this idea.
Tolerance is the collective term for a variety of mechanisms used by the human
immune system to prevent autoimmunity. Primary tolerance occurs during immune
cell development in the bone marrow, and acts to weed out developing immune
cells that generate autoreactive antibodies or other autoimmune responses.
Secondary tolerance, which is the main focus here, acts to mitigate the effects
of autoreactive responses that are already in existence. One of the mechanisms
of secondary tolerance is the development of regulatory T-cells, which act to
tone down immune responses to particular antigens.
Viruses can exploit tolerance in order to evade the immune system, and this
notably occurs with HIV. The viral envelope protein is sufficiently similar in
form to a human protein (histone H2A) that an effective antibody response is
blocked by tolerance mechanisms, and people with certain autoimmune conditions
compromising these tolerance mechanisms actually mount a more effective antibody
response against HIV.
(https://www.sciencedirect.com/science/article/abs/pii/S0952791516301522)
Increasing tolerance to a pathogen can paradoxically decrease severe disease,
when severe disease involves an immune overreaction/cytokine storm rather than
actual viral tissue damage. Such is the case with most cases of severe Covid-19
that lead to hospitalization and death.
(https://pubmed.ncbi.nlm.nih.gov/33391477/) However, this protective effect
comes with trade-offs. When coronavirus-family infections were studied in mice,
regulatory T-cells prevented severe immunogenic illness but increased the risk
of viral persistence and chronic infection. Furthermore, regulatory T-cell
activation can non-specifically dampen immune response to other pathogens, leading
to increased incidence of secondary infections.
(https://www.mdpi.com/1999-4915/4/5/833/htm)
The main biochemical difference between genetic vaccines and conventional
vaccines is that the former present protein antigens to the immune system on
the surface of human cells, while the latter present antigens on inactivated
viruses or other inert injected particles. Furthermore, when genetic vaccines
“infect” a large number of muscle cells, or vessel wall cells, or heart cells,
causing them to produce spike protein, the immune system creates conflicting
signals. The generated antibodies say “kill that foreign object!” while the
self-recognition systems say “that thing just showed up on a bunch of our
cells, must be OK!” For this reason, we might expect genetic vaccines to be
more likely to induce anti-autoimmunity tolerance mechanisms.
Interestingly, there is an mRNA vaccine in development that is specifically
designed to induce tolerance as a treatment for autoimmune disease through
activation of regulatory T-cells. The Nature paper describing that work
curiously includes the following paragraph: “Sahin and colleagues have clearly
demonstrated the potential of RNA lipoplex vaccines to deliver a
non-inflammatory form of an mRNA vaccine encoding a self antigen to prevent and
limit autoimmune disease in mice. It is noteworthy that m1ĪØ-containing mRNA is also used for the COVID-19 mRNA vaccine, indicating
that the pro- versus anti-inflammatory nature of m1ĪØ mRNA vaccines can be modulated depending on the specific antigen and
specific encapsulating lipid formulation. In the case of the BNT162b2 vaccine
for COVID-19, the antigen is a foreign protein formulated in an
immunostimulatory lipid nanoparticle. In the present study, the antigen is a
self protein delivered in a non-immunogenic lipoplex formulation, and an extra
mRNA purification step removes any residual immunostimulatory molecules. This
method allows antigen presentation in the absence of inflammation and
co-stimulation, preferential expansion of pre-existing T(reg) cells, and
possibly also their de novo development.”
(https://www.nature.com/articles/s41587-021-00880-0)
In other words, they claim that the immune response to an mRNA vaccine can be
switched between tolerance and immunity by choosing a self or foreign protein
and selecting a pro- or anti-inflammatory lipid formulation for the
encapsulation. I highly doubt that it’s that simple, and I strongly suspect
that unintentional induction of partial tolerance is a likely side effect of
any genetic vaccine.
Conveniently, in the case of Covid-19, it turns out that tolerance is
protective against severe disease, and indeed some treatment efforts have
focused specifically on enhancing immune tolerance
(https://journals.ekb.eg/article_92759.html). However, immune tolerance may
also be associated with prolonged virus shedding
(https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30273-X/fulltext).
If the genetic vaccines do indeed induce partial immune tolerance, that could
help to explain their impressive efficacy against the sort of immune
overreaction that leads to hospitalization and death, while also explaining
their comparative weakness in preventing infection and transmission of the
virus. If “long covid” is, as many scientists suspect, partially induced by
autoreactive antibodies, then it would also make sense that genetic vaccines
could reduce or eliminate those symptoms by inducing tolerance. This could help
to explain the phenomenon that vaccination sometimes alleviates long covid, and
also reduces the incidence of long covid in breakthrough infections.
This is an eminently testable hypothesis that can be explored by examining
regulatory T-cell responses (or other immune tolerance responses) following
vaccination. To date, I can find no evidence that anyone has done this, but I
would hope that it will happen in the near future, and the results will be
illuminating.
Tolerance is not an on/off phenomenon but rather a wide spectrum ranging from
the complete immune acceptance of most of our own proteins to the extreme
reactogenicity of a serious peanut or bee sting allergy. Tolerance mechanisms
can coexist with immunity mechanisms, such that tolerance begins to become
apparent as the level of neutralizing antibodies declines. And to be clear, I
am not hypothesizing that the genetic Covid-19 vaccines function by virtue of
inducing tolerance. It has been well-demonstrated that they induce a strong
neutralizing antibody response. I am instead suggesting that they may *also* be
inducing partial tolerance, and that this effect may help to explain strong
protection against severe (immune overreaction) disease, high rates of illness
transmission in high-vax areas, and possibly also significant declines in
immunity after 4-6 months despite continuing high antibody levels.
If indeed the genetic Covid-19 vaccines are inducing partial tolerance, we can
make certain predictions:
1. Genetic vaccines will be extremely effective at preventing severe
disease, but much less effective in terms of preventing infection. (True)
2. As vaccine immunity wanes, protection against cytokine-storm-type severe
disease will be maintained. (Seems to be true)
3.
As vaccine
immunity wanes, vaccinated people will increasingly carry and spread the virus,
and population-level viral prevalence will rise in areas with a high uptake of
genetic vaccines. (True) Vaccinated people will be more likely to be
asymptomatic carriers. (True,
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00460-6/fulltext)
4.
This will
lead to a significant wave of illness transmission which will
disproportionately affect unvaccinated people (who are not protected against
severe disease). (True right now across the US and much of the world)
5. Booster shots will further increase tolerance, leading to an increased
level of disease prevalence across the population. (True in Israel)
6.
As immunity
wanes and new antibody-resistant variants emerge, vaccinated people will be
more vulnerable to long-term/chronic infection with high viral loads. Due to
the protective effects of tolerance this will likely manifest not as typical
severe Covid-19 illness (pneumonia, ventilators, cytokine storms, multiorgan
failure) but rather as spike protein toxicity. So we should watch for an
increase in clotting, strokes, heart attacks, myocarditis, neurological
problems, etc. Vaccinated patients dying of these conditions may not be tested
for Covid-19 and so likely will not be counted as covid deaths, and the myth of
vaccine efficacy may persist based on the original definition of “preventing
severe Covid-19 disease” even as we experience a wave of mysterious illness and
death. Furthermore, vaccinated people may be more vulnerable to other
infections due to regulatory-T-cell mediated general immune suppression. Should
ADE develop, with non-neutralizing antibodies facilitating enhanced infection
or direct infection of immune cells, tolerance could well lead to further
exacerbation. However tolerance could also provide protection against cytokine
storm-type reactions and accelerate the evolution of SARS-CoV2 into an endemic
human pathogen, so the long-term effect of tolerance is uncertain.
7.
Contrary to
the shrill claims of the fearful, vaccinated people will present a much greater
danger than unvaccinated people in terms of asymptomatic transmission and
evolution of new variants.
8.
There are
likely to be significant differences between the vaccines. In particular, the
two-shot series would be expected to induce greater tolerance, and possibly
also greater tolerance will be evident in countries with a shorter interval
between the two shots. Countries that utilized inactivated-virus vaccines are
probably less likely to see tolerance effects, although they may still
encounter ADE or other problems down the road.
This hypothesis presents a scenario of vaccine failure that first appears as
success (because tolerance prevents severe disease), that explains the trends
currently observed (unexpectedly high illness rates in high-vax areas), and
that potentially portends a troubling future without invoking the
still-hypothetical ADE. As with JMG’s original hypothesis, time will tell…
Mark L
UPDATE: One of our own, El Gato, published a VERY prophetic article on
Sep 16:
274 Comments
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14 hr agoLiked by Igor Chudov There is graphene oxide in those shots. It
is shedding off onto those of us who didn't take the shots. I have been sick
for 15 months until recently. I found a doctor who hasn't sold his soul to
the CDC. They found graphene oxide in my blood. It had my white blood cells
suppressed. I am on a protocol to remove g.o from my blood. It is working!! I
would love to talk to someone who can help me get this protocol out to the
public so people can get help. |
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14 hr agoLiked
by Igor Chudov I would reach out to FLCCC. Dr's P.Kory and Paul Marik. They have all
kinds of protocols from prevention to v injured. Good Luck. |
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14 hr agoLiked
by Igor Chudov Tell us more, please. |
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Ditto thAT!! Yes, pLease Jennifer, would love to hear more of your story!! Like,
how g.o. was found in your blood? Was it a simple blood test? Your symptoms?
The protocol?? Share awayyy... ; ) Incredibly intriguing as I too have been experiencing oddities after
being around the jab'd - low fever for days, mild sore throat, increased
cough, and just general feeling unwell. Actually going to my GP tomorrow for
blood work, after a 2wk run of fever, aFter going ouT to dinner for first
time since start of pLandemic with out-of-town jab'd family, jab'd siblings,
and gathering following day as well. Been on coNvid prophylactic protocol,
even did 5 day course Ivermectin/early trtmnt protocol.!. I feel like I sound absolutely crAzy relating my symptoms to the
jab'd, but how many times can coincidence happen, ya know!?! I aM immunocompromised (MS), don't have regular human contact, still
haven't yet reunited with my production plant working jab'd husband - just
me, my two crAzy Bengal cats, and all you like minded folks and communities
that help keep me sane. Sighhh...pardon my novel. : ] Also - IncrEdible piece Igor!!! Endless thanks to you!!! |
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It started after I was
exposed to 63 vaccinated elderly residents in a nursing home. It started with headaches, which I rarely get. I began having extra
menstrual cycles. I found a knot in my breast. I made an appointment with my
family doctor. He did blood work that only revealed high estrogen levels. The
knot ended up being a cyst. This doctor told me he suspected I was
experiencing V shedding. So I began to read everything I could find. Some
doctors call it transferring. I had to
quit my job. For the next 14 months I had 2 and 3 full week periods every
month. 2 months ago my BP dropped down to 90/50. I have a friend who works
with AFLDS citizen corp group. He told me the name of a clinic that treats
"hundreds" of women who have the same symptoms. As I waited for my
appointment I continued to read. I found an article that suggested several supplements. Quercetin. D3, zinc, NAC, milk thistle,
astaxanthin, ivermectin and HCQ. So I began those. The doctor added more.
My blood was beginning to coagulate so
I'm taking nattokinase for that. Ovex
to stop the bleeding. AC
Carbamide, glutathione and chelation therapy. I have now gone 22 days without bleeding. I have my energy back. No
more feeling heavy and weighted down. The last 3 mornings I have woke up
without feeling hungover. I am
also being extra careful not to touch or get in anyones breathing space. |
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I specifically asked them to check my blood for graphene oxide. I have
read in several places and heard a few doctors say they believe it is g.o. So
I asked them to check. That was the only toxin found in my blood work. |
12 replies
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I am sorry that you went through that and glad that you are feeling
better. Thank
you for sharing your experience and learning. |
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Shedding
is not a myth. You do not sound crazy
at all. |
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ThAnk you for that!!❤️ |
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Jennifer I did not get vaxxed. I am soon to drive medical patients To their appointments, my wife is Doing this too. I suspect most people Will have been vaxxed … I’d like to know about prevention Or any practical things we can do If you have any words of advice Thanks. |
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Read my reply above. The best
advice I can give, other than the regimen I am on, is to don't touch them. I
would crack their window if riding with them. I am now getting calls from men
who are also bleeding. |
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Okay, I’m just gonna go ahead and ask... bleeding from where? |
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Thanks for asking that question. |
1 reply
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Vaginal bleeding. I have
an uncle who started bleeding out of his penis after his wife took the
booster shot. I'm reading stories of people getting nose bleeds, flu like
symptoms, rashes.... Before I left the nursing home,
80-100 year old women started having periods! I reported every incident
to the nurses. Not a single one of them questioned or put two and two
together. They simply called the doc and asked him to put the residents on
hormones. |
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HOly heck!! That's insane. Thank goodness for you getting the good
medical attention you did!! |
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Really bleeding? I will use widow. Was suggested using silver mask Ivermectin and other vitamins taking. |
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Personally,
I think keeping our immune system as strong as possible is our best defense.
I am using ivermectin daily, so are my family members. |
1 reply
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Hi Jennifer glad to hear you are able to remove g.p from your blood. If you do not
mind, I am curious about the protocol you are on. I noticed extreme tiredness
and ichiness in my nose when I socialise with vaccinated people. I am
unvaccinated and never had covid but I am suspecting that I might
"have" it without actually having symptoms hence curiousity about
protocol. |
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14 hr agoLiked by Igor Chudov Numerous studies have now clearly documented a noticeably dampened
T-cell 8+/4+ response to other viruses and cancer cells, in part because the
pseudouridine substitution in the mRNA vaccine negatively affects the
toll-like receptors 3, 7, and 8. In the long-term, this is especially
worrying with respect to cancer, and pathologists
in several independent labs in a number of countries are witnessing an
explosion in unusual cancers among the vaccinated. GPs, too, are
expressing concern over unusual and far more frequent types of cancer, even
in young people, than they had ever witnessed before in their careers. One
doctor in Florida noted that he had seen 5 younger patients this year alone
with an unusual type of kidney cancer. He had seen only one such case in the
prior years he had been practicing. German
pathologists has used the terms "turbo cancer" to describe the
sudden re-emergence of particularly aggressive forms of cancer in vaccinated
patients that had been successfully treated and were in remission prior to
vaccination. The same types of susceptibility in the vaccinated are now being
documented for Epstein-Barr, Herpes simplex, Herpes zoster, and several other
viruses. |
24 replies by
Igor Chudov and others
