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Antiviral activity of plant juices and green tea
against SARS-CoV-2 and influenza virus in vitro
Bruno Frank, Carina Conzelmann, Tatjana Weil, Rüdiger Groß, Peggy Jungke, Maren Eggers, Janis A. Müller, Jan Münch, Uwe Kessler
doi: https://doi.org/10.1101/2020.10.30.360545
Abstract
Many plant juices, extracts
and teas have been shown to possess antiviral activity. We here analyzed the
virucidal activity of black
chokeberry (Aronia melanocarpa), pomegranate (Punica granatum), and elderberry (Sambucus nigra) juice,
as well as green tea (Camellia sinensis) against
different respiratory viruses. We found that all tested plant derived products
effectively inactivated influenza virus, whereas only chokeberry juice
diminished SARS-CoV-2 and vaccinia virus infectivity. None of the products
inactivated non-enveloped human adenovirus type 5. Thus, black chokeberry juice
exerts virucidal activity against different enveloped viral pathogens
under in vitro conditions.
Whether application of virucidal juices or green tea as oral rinses may lower viral
loads in the oral cavity in vivo remains to be
evaluated.
Competing Interest Statement
B.F. and U.K. are partners of CogniVerde GmbH Gross-Umstadt, Germany.
R.G. acted as a consultant of CogniVerde GmbH, Gross-Umstadt, Germany.
Paper in collection COVID-19 SARS-CoV-2 preprints from medRxiv
and bioRxiv